AAAS: THE LIVING ENVIRONMENT: CELLS - Most cells function best within a narrow range of temperature and acidity
Most cells function best within a narrow range of temperature and acidity. At very low temperatures, reaction rates are too slow. High temperatures and/or extremes of acidity can irreversibly change the structure of most protein molecules. Even small changes in acidity can alter the molecules and how they interact. Both single cells and multicellular organisms have molecules that help to keep the cell's acidity within a narrow range.